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Atypical plasma cells in alpha‐chain disease
Author(s) -
Veloso Fernando Tavarela,
Vaz Saleiro José,
Oliveira Alberto Ortigão,
De Freitas António Falcão
Publication year - 2006
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19830701)52:1<79::aid-cncr2820520116>3.0.co;2-w
Subject(s) - plasma cell , ultrastructure , medicine , alpha chain , pathology , multiple myeloma , biopsy , alpha (finance) , disease , bone marrow , surgery , construct validity , receptor , patient satisfaction
Pathologic features of the jejunal mucosa of a patient with alpha‐chain disease in its early transition to malignant stage, are described. Ultrastructural alterations were seen in some plasma cell, close similar to those described in myeloma plasma cells. Ultrastructural studies of biopsy specimens in alpha‐chain disease, may permit recognition of its early transition to malignant stage and thereby encourage earlier use of cytotoxic drugs. Cancer 52:79‐82, 1983.