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Unresectable carcinoma of the bladder
Author(s) -
Montie James E.,
Whitmore Willet F.,
Grabstald Harry M.,
Yagoda Alan
Publication year - 1983
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19830615)51:12<2351::aid-cncr2820511231>3.0.co;2-2
Subject(s) - medicine , laparotomy , cystectomy , urinary diversion , urinary bladder , bladder cancer , natural history , carcinoma , urinary system , chemotherapy , surgery , urology , cancer
The clinical courses of 119 patients with unresectable bladder cancer were analyzed. All patients had a laparotomy with the intent of cystectomy. TN categorization postlaparotomy did not identify variables significantly influencing the natural history of the disease, although previous definitive irradiation or T4 a N x–4 categories were associated with especially poor survival. T category correlated more closely with survival than did N category. Supravesical urinary diversion palliated patients with urinary symptoms and/or bilateral ureteral obstruction. Patients without compelling urinary symptoms at the time of laparotomy uncommonly needed diversion later. Pelvic irradiation and systemic chemotherapy available in the interval from 1961 to 1976 had minimal if any demonstrable effect on the time course of the disease.