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Primary radiation therapy for early breast cancer
Author(s) -
Harris Jay R.,
Hellman Samuel
Publication year - 1983
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19830615)51:12+<2547::aid-cncr2820511328>3.0.co;2-#
Subject(s) - medicine , radiation therapy , mastectomy , breast cancer , subclinical infection , primary treatment , surgery , cancer , primary tumor , metastasis
Primary radiation therapy for early breast cancer is a combination of limited breast surgery for the removal of gross disease, and moderate doses of radiation for the control of residual subclinical disease. The results from retrospective studies using primary radiation therapy indicate that high levels of local tumor control with good cosmetic results can be achieved. Preliminary results from a prospective randomized clinical trial indicate that radical mastectomy and primary radiation therapy result in equivalent survival rates. Primary radiation therapy is a reasonable alternative to mastectomy when adequate surgical and radiotherapeutic expertise is available to deliver this treatment.