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Androgen related primary hepatic tumors in non‐Fanconi patients
Author(s) -
Westaby D.,
Portmann B.,
Williams Roger
Publication year - 1983
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19830515)51:10<1947::aid-cncr2820511034>3.0.co;2-5
Subject(s) - medicine , androgen , adenoma , pathology , gastroenterology , hormone
Three cases of androgen related primary hepatic tumor in non‐Fanconi patients are described in whom detailed information is available concerning histologic changes and clinical course over long periods. Two patients presented with hepatic rupture and hemoperitoneum requiring surgical intervention. In one case histologic assessment showed a hepatic adenoma which has almost completely regressed over four years since androgen withdrawal. In two patients there was a degree of nuclear pleomorphism not seen in ‘spontaneous’ adenomas and following androgen withdrawal there has been no evidence of progression or of metastases although the tumor has not regressed over a follow‐up period of two years.