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Radical mastectomy versus radical mastectomy plus internal mammary dissection. Ten year results of an international cooperative trial in breast cancer
Author(s) -
Lacour Jean,
Le Monique,
Caceres Eduardo,
Koszarowski Tadeus,
Veronesi Umberto,
Hill Catherine
Publication year - 1983
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19830515)51:10<1941::aid-cncr2820511032>3.0.co;2-t
Subject(s) - medicine , dissection (medical) , breast cancer , mastectomy , surgery , radical mastectomy , modified radical mastectomy , mammary gland , randomized controlled trial , cancer , significant difference
A multicentric randomized trial evaluated the interest of internal mammary dissection on operable breast cancer patients. One thousand four hundred and fifty‐three patients were included in the study and were followed for ten years. There is no difference in survival or in relapse‐free survival between the two groups. There were significantly more local recurrences in the group without internal mammary dissection, but these recurrences occurred mainly on patients who developed metastases. A great difference between centers was observed in the number of nodes examined and there is therefore a difference in the prognostic value of the number of nodes invaded.