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Alfred P. Sloan Jr. Award. The epidermal growth factor (EGF)
Author(s) -
Cohen Stanley
Publication year - 1983
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19830515)51:10<1787::aid-cncr2820511004>3.0.co;2-a
Subject(s) - epidermal growth factor , isolation (microbiology) , medicine , epidermal growth factor receptor , cancer research , action (physics) , transformation (genetics) , microbiology and biotechnology , biology , bioinformatics , cancer , genetics , receptor , physics , quantum mechanics , gene
This review summarizes briefly some of the historical aspects of the discovery, isolation, and mode of action of epidermal growth factor (EGF). Also considered are some of the key experiments which relate the biochemical mechanisms of EGF action to the mechanism involved in oncogenic transformation by the retroviruses.