Premium
Prognostic factors in local surgical treatment of invasive bladder cancer, with special reference to the presence of urothelial dysplasia
Author(s) -
Wolf Hans,
Højgaard Knud
Publication year - 1983
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19830501)51:9<1710::aid-cncr2820510925>3.0.co;2-n
Subject(s) - medicine , urothelial cancer , bladder cancer , dysplasia , cancer , bladder neoplasm , oncology , urology , general surgery
Thirty‐three patients with bladder cancer of categories pT 1 or pT 2 were treated by transurethral resection alone. At the initial diagnosis random preselected site mucosal biopsies were obtained to demonstrate the presence or absence of concomitant urothelial dysplasia. A statistically significant ( P < 0.01) relationship was found between the presence or absence of concomitant urothelial dysplasia and the development of new occurrence or the absence of recurrence at cystoscopic follow‐up. Four of six patients with concomitant carcinoma in situ developed invasive bladder cancer within 6 months demonstrating the serious prognostic significance of this entity. Thus, the presence or absence of concomitant urothelial dysplasia at the initial diagnosis of invasive bladder cancer seems to be an important prognostic factor for future new occurrences.