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Definitive irradiation of T 1 ‐T 4 N 0 larynx cancer
Author(s) -
Chacko Donna C.,
Hendrickson Frank R.,
Fisher Alan
Publication year - 1983
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19830315)51:6<994::aid-cncr2820510605>3.0.co;2-f
Subject(s) - medicine , larynx , radiation therapy , cancer , salvage therapy , surgery , cancer recurrence , oncology , radiology , chemotherapy
The use of definitive irradiation in T 1 ‐T 4 N 0 larynx cancer was reviewed in 236 patients at Rush‐Presbysterian‐St. Luke's Medical Center in Chicago. Recurrence‐free survival for all stages was 86% at five years. Ultimate recurrence‐free survival, including successful surgical salvage, was 91% at five years. The data described herein and the literature reviewed support the recommendation for definitive radiation therapy for T 1 and T 2 N 0 larynx cancer of any site. T 3 lesions may also be reasonably treated with radiation therapy initially, reserving surgery for salvage. However, more data are needed to accurately identify the T 3 larynx cancer patients most suited for radiation therapy.