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Primary leptomeningeal presentation of T‐cell lymphoma: Report of a patient and review of the literature
Author(s) -
Marsh William L.,
Stevenson Dennis R.,
Long Harry J.
Publication year - 1983
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19830315)51:6<1125::aid-cncr2820510625>3.0.co;2-u
Subject(s) - medicine , presentation (obstetrics) , lymphoma , dermatology , pathology , surgery
Although secondary leptomeningeal lymphoma is relatively common, primary leptomeningeal lymphoma is rare. We report a patient with the extremely unusual clinical and pathologic presentation of a primary T‐cell lymphoma of the leptomeninges. Diagnosis was established by morphologic and immunologic studies of cerebrospinal fluid (CSF) and brain biopsy. The leptomeningeal lymphoma responded well to intrathecal chemotherapy and irradiation but th epatient has severe residual motor paralysis. The clinical and pathological features of primary and secondary central nervous system (CNS) lymphoma are reviewed in reference to this most unusual patient.