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Complete recovery of histiocytic medullary reticulosis‐like syndrome in a child with acute lymphoblastic leukemia
Author(s) -
Yin J. A. Liu,
Kumaran T. O.,
Marsh G. W.,
Rossiter M.,
Catovsky D.
Publication year - 1983
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19830115)51:2<200::aid-cncr2820510204>3.0.co;2-c
Subject(s) - medicine , histiocyte , lymphoblastic leukemia , medullary cavity , leukemia , chemotherapy , acute lymphocytic leukemia , immunology , pathology
A 6‐year‐old boy with acute lymphoblastic leukemia (ALL) developed a haemophagocytic syndrome resembling histiocytic medullary reticulosis (HMR) but made a complete recovery on supportive treatment. This was subsequently found to have been associated with a parainfluenzal infection. It is suggested that HMR in immunocompromised hosts may represent a reactive process to an opportunistic viral infection and that the use of chemotherapy in these patients may be deleterious.