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Endoscopic diagnosis of early gastric cancer by the endoscopic congo red‐methylene blue test
Author(s) -
Tatsuta Masaharu,
Okuda Shigeru,
Tamura Hiroshi,
Taniguchi Haruo
Publication year - 1982
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19821215)50:12<2956::aid-cncr2820501242>3.0.co;2-a
Subject(s) - congo red , methylene blue , medicine , cancer , pathology , biopsy , gastroenterology , biology , chemistry , biochemistry , organic chemistry , adsorption , photocatalysis , catalysis
The endoscopic Congo red test combined with dyeing with methylene blue was performed in 85 patients with early gastric cancer (94 lesions). Results revealed that gastric cancer bleached the Congo red and methylene blue sprayed over their surface and this appeared in sharp contrast to the red‐colored mucosa of unaffected areas. Grossly, polypoid and flat types, and histologically differentiated adenocarcinomas bleached the dyes more frequently and more intensely than depressed and undifferentiated adenocarcinomas. Thus the spread of cancerous growth could be judged rather accurately and so the target area could be reached by biopsy in cases where there were few if any visual signs of abnormality.