Premium
Mucinous carcinomas of the colon and rectum and their relation to polyps
Author(s) -
Sundblad Alberto S.,
Paz Ricardo A.
Publication year - 1982
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19821201)50:11<2504::aid-cncr2820501141>3.0.co;2-a
Subject(s) - rectum , medicine , general surgery , relation (database) , gastroenterology , computer science , database
A study of 44 mucinous carcinomas (MC) from a series of 324 colorectal cancers was made (221 surgical resections and 103 endoscopic biopsies). This study showed that MC were associated, in a significantly higher proportion when compared to non MC, with polypoid adenomas of different kinds (hyperplastic polyps not included), in other segments of the surgical specimen ( P < 0.001). MC originated from adenomas, particularly villous, but also mixed and tubular, in a significantly higher proportion than non‐MC ( P < 0.001). Carcinomas arising from adenomas were mucinous in 11/14 cases. The type of adenomas from which MC arose were characterized by usually having areas with a particular arborizing mucus hyperplasia. At the time of resection, MC had metastases (Stages C and D) more frequently then non MC ( P < 0.02).