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Chemotherapy of advanced salivary gland neoplasms
Author(s) -
Posner Marshall R.,
Ervin Thomas J.,
Weichselbaum Ralph R.,
Fabian Richard L.,
Miller Daniel
Publication year - 1982
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19821201)50:11<2261::aid-cncr2820501105>3.0.co;2-e
Subject(s) - medicine , cyclophosphamide , bleomycin , salivary gland , chemotherapy , mucoepidermoid carcinoma , methotrexate , regimen , oncology , pathology , surgery
Fourteen patients with advanced salivary gland malignancies were treated with combination chemotherapy. Five of 13 patients responded to cyclophosphamide and adriamycin and two patients in the responding groups underwent further potentially curable treatment, rendering them disease‐free. Three patients with mucoepidermoid carcinoma failed to respond to this regimen, but two of three patients treated with a combination of cisplatinum, bleomycin and methotrexate responded. The potential role for chemotherapy in the treatment of salivary gland malignancies is discussed.