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Angioimmunoblastic lymphadenopathy progressing to immunoblastic lymphoma with prominent gastric involvement an immunohistochemical study of two cases
Author(s) -
Bauer Thomas W.,
Mendelsohn Geoffrey,
Humphrey Richard L.,
Mann Risa B.
Publication year - 1982
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19821115)50:10<2089::aid-cncr2820501020>3.0.co;2-5
Subject(s) - medicine , pathology , lymphoma , immunohistochemistry , autopsy , lymph node , lymph
Two unusual cases of angioimmunoblastic lymphadenopathy with dysproteinemia (AILD), with progression to immunoblastic lymphoma (IL) and prominent gastric involvement are presented, and detailed immunohistologic studies described. In one case, Bence Jones proteinuria of the kappa type was observed during the course of AILD and was identified immunohistochemically in lymph node biopsy specimens and at autopsy. The potential significance of an M component and the importance of recognizing gastric involvement by AILD are discussed.

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