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Agnogenic myeloid metaplasia preceded by repeated leukemoid reactions and persistent acquired Pelger‐Huët anomaly of granulocytes. Case report with review of acquired Pelger‐Huët anomaly
Author(s) -
O'Donnell J. R.,
Farrell M. A.,
Fitzgerald M. X.,
O'Connell L. G.
Publication year - 1982
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19821015)50:8<1498::aid-cncr2820500809>3.0.co;2-2
Subject(s) - leukemoid reaction , medicine , anomaly (physics) , pathology , myeloid , immunology , physics , condensed matter physics
A case report of agnogenic myeloid metaplasia (AMM) is presented in which a patient had a preliminary 18‐month period characterized by leukemoid reactions to repeated infections alternating with normal health, throughout which an acquired Pelger‐Huët anomaly persisted. This is the only reported case of the anomaly as a premonitory hematologic marker of AMM. The literature concerning the acquired Pelger‐Huët anomaly is reviewed.