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Significance of a (4; 11) translocation in acute lymphoblastic leukemia
Author(s) -
Esseltine D. W.,
Vekemans M.,
Seemayer T.,
Reece E.,
Gordon J.,
Whitehead V. M.
Publication year - 1982
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19820801)50:3<503::aid-cncr2820500320>3.0.co;2-5
Subject(s) - chromosomal translocation , lymphoblastic leukemia , medicine , philadelphia chromosome , leukemia , abnormality , acute leukemia , chromosomal abnormality , cancer research , chromosome , karyotype , immunology , genetics , biology , gene , psychiatry
This report describes a case of null cell congenital acute lymphoblastic leukemia associated with a (4;11) translocation. This chromosome abnormality is associated with acute lymphoblastic leukemia and probably more specifically with congenital acute lymphoblastic leukemia. A review of the literature is presented.