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Calcifying synovial sarcoma
Author(s) -
VarelaDuran Juan,
Enzinger Franz M.
Publication year - 1982
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19820715)50:2<345::aid-cncr2820500231>3.0.co;2-y
Subject(s) - medicine , synovial sarcoma , calcification , sarcoma , pathology , incidence (geometry) , metaplasia , soft tissue , physics , optics
Analysis of the clinicopathological features and the available follow‐up data in 32 patients with extensively calcified synovial sarcoma revealed an age incidence and anatomic distribution similar to that of ordinary synovial sarcomas without or with minimal calcification, but indicated a more favorable survival. The median age of the 32 patients of this series was 26 years; the predominant location of the tumor was the soft tissues of the lower extremities; its average size was 4.6 cm (range, 1.5–20 cm). All of the tumors showed a focal biphasic cellular pattern and exhibited roentgenographic or microscopic evidence of extensive calcification and/or osseous metaplasia. Of the 26 patients with follow‐up information (average, 8.9 years) 17 were alive and well and six had died of their disease, two after 7 and 19 years. Three additional patients were living with no signs of disease 1 1/2, 2 1/2, and three years after diagnosis, respectively. The five‐year survival rate of 82.6 percent of this series is considerably better than the reported five‐year survival rates of synovial sarcoma which range from 25–51%.