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Low‐grade adenocarcinoma of the nasal cavity and paranasal sinuses
Author(s) -
Heffner Dennis K.,
Hyams Vincent J.,
Hauck Kenneth W.,
Lingeman Carolyn
Publication year - 1982
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19820715)50:2<312::aid-cncr2820500225>3.0.co;2-z
Subject(s) - medicine , nasal cavity , mucoepidermoid carcinoma , paranasal sinuses , adenoid cystic carcinoma , pleomorphism (cytology) , adenocarcinoma , pathology , adenoid , carcinoma , cancer , anatomy , immunohistochemistry
The pathologic features and the behavior of 50 cases of adenocarcinoma (excluding adenoid cystic carcinoma and mucoepidermoid carcinoma) of the sinonasal tract are presented. The cases were divided on histologic grounds into 23 low‐grade and 27 high‐grade neoplams. The low grade lesions had a well developed glandular pattern throughout, very uniform nuclei, and minimal mitotic activity. The high grade tumors had a less uniform glandular pattern, commonly with solid or sheet‐like areas, manifested nuclear pleomorphism, and generally had a higher mitotic rate. The low‐grade group had a prognosis markedly better than the high‐grade group. Since the literature tends to consider all sinonasal adenocarcinomas as relentlessly progressive neoplasms with poor prognosis, it is important to recognize this category of low grade neoplasm in order that treatment and prognostication can be better related to their behavior.