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Plasmacytoma of the colon case report with lambda light chain, demonstrated by immunoperoxidase studies
Author(s) -
Gleason Terrence H.,
Hammar Samuel P.
Publication year - 1982
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19820701)50:1<130::aid-cncr2820500124>3.0.co;2-o
Subject(s) - immunoperoxidase , plasmacytoma , pathology , gastrointestinal tract , medicine , lesion , immunoglobulin light chain , multiple myeloma , immunology , antibody , monoclonal antibody
A case of solitary extramedullary plasmacytoma in the transverse colon of a 20‐year‐old woman is reported. This case is unusual in that the plasmacytomas are only rarely observed in the gastrointestinal tract and are especially uncommon in the colon and in young women. The lesion was composed of pleomorphic plasma cells and contained areas of extracellular amyloid deposition. Its neoplastic nature was verified by the use of immunoperoxidase studies which were positive only for lambda light chain. The subject of gastrointestinal plasmacytomas and the use of immunoperoxidase studies on plasmacytic lesions are discussed. cancer 50:130‐133, 1982.