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The risk of spontaneous pneumothorax in patients with osteogenic sarcoma and testicular cancer
Author(s) -
Smevik Bjarne,
Klepp Olbjørn
Publication year - 1982
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19820415)49:8<1734::aid-cncr2820490833>3.0.co;2-k
Subject(s) - medicine , pneumothorax , chemotherapy , lung cancer , sarcoma , surgery , lung , testicular cancer , retrospective cohort study , pathology
Seven cases of unilateral, spontaneous pneumothorax were found in a retrospective study of 63 patients with osteogenic sarcoma who were admitted to The Norwegian Radium Hospital (NRH) in the period 1970–1977. The relative risk of pneumothorax developing doubled, from 7–14%, after the introduction of chemotherapy for this disease at NRH. This difference was not statistically significant. Pneumothorax developed in two of 18 patients (11%) with lung metastases who never received chemotherapy. Pneumothorax occurred in four of 19 patients (21%) treated with chemotherapy for manifest lung metastases, and in one of eight patients (13%) who received adjuvant chemotherapy, but in whom lung metastases developed later. Pneumothorax did not develop in 79 patients treated with chemotherapy for disseminated testicular cancer, despite the fact that 82% of these patients had manifest lung metastases.