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Prior irradiation and the development of coexistent differentiated thyroid cancer and hyperparathyroidism
Author(s) -
Prinz Richard A.,
Barbato Anthony L.,
Braithwaite Susan S.,
Brooks Marion H.,
Lawrence Ann M.,
Paloyan Edward
Publication year - 1982
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19820301)49:5<874::aid-cncr2820490509>3.0.co;2-d
Subject(s) - medicine , hyperparathyroidism , thyroid cancer , thyroid , cancer , oncology , pathology
Twelve patients with coexistent well‐differentiated thyroid carcinoma and primary hyperparathyroidism were studied to determine the frequency of previous radiation exposure. Eight were found to have received prior irradiation. External radiation was administered to the head and neck region for benign conditions such as tonsillar enlargement, acne, scrofula, and thyroid enlargement. One patient received 131 I therapy for carcinoma of the thyroid. The observation that 67% of the patients in this series had previous radiation to the head and neck strongly implicates radiation exposure in the development of coexistent well‐differentiated thyroid carcinoma and hyperparathyroidism.