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Myoepithelioma of salivary glands: Report of 23 cases
Author(s) -
Sciubba James J.,
Bran Robert B.
Publication year - 1982
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19820201)49:3<562::aid-cncr2820490328>3.0.co;2-6
Subject(s) - myoepithelioma , myoepithelial cell , minor salivary glands , salivary gland , medicine , pathology , submandibular gland , ultrastructure , parotid gland , myofilament , anatomy , immunohistochemistry , myocyte
Abstract Twenty‐three neoplasms arising in major and minor salivary glands have been found to be composed of two types of myoepithelial cells–‐the plasmacytoid and spindle‐cell form. Twelve of these were located within the parotid gland and the submandibular gland and intraoral minor salivary glands accounted for five each. A solitary example was found within the upper lip. Sixteen (70%) of the cases were of the spindle‐cell type, four (17%) were composed of plasmacytoid cells, and three cases (13%) contained both cell forms in approximately equal quantity. Differences in behavior, recurrence rate, frequency, age of the patient, and location were not related to cell type. Ultrastructural analysis of selected cases showed myofilament aggregation patterns to vary between the two subtypes. Previously published cases confirmed by electron microscopy have been reviewed and compared with the 23 cases reported. Conservative surgical management is curative. Follow‐up information on 16 cases is presented.