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Follow‐up study of thymomas with special reference to their clinical stages
Author(s) -
Masaoka Akira,
Monden Yasumasa,
Nakahara Kazuya,
Tanioka Tsuneo
Publication year - 1981
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19811201)48:11<2485::aid-cncr2820481123>3.0.co;2-r
Subject(s) - medicine , stage (stratigraphy) , thymoma , surgery , survival rate , radiation therapy , metastasis , capsule , cancer , paleontology , botany , biology
Follow‐up data were obtained for 96 cases of thymoma. The one‐year survival rate was 84.3%, the three‐year 77.1%, the five‐year 74.1%, and the ten‐year 57.1%. The five‐year survival rate of total resection group was 88.9%; that of non‐radically treated group was 44.4%. Clinical stages were defined: Stage I—macroscopically encapsulated and microscopically no capsular invasion; Stage II—1. macroscopic invasion into surrounding fatty tissue or mediastinal pleura, or 2. microscopic invasion into capsule; Stage III—macroscopic invasion into neighboring organ; Stage IVa—pleural or pericardial dissemination; Stage IVb—lymphogenous or hematogenous metastasis. Five‐year survival rates of each clinical stage were 92.6% in Stage I, 85.7% in Stage II, 69.6% in Stage III, and 50% in Stage IV. Recurrence after total resection was found in six of 69 cases. Seven of 13 patients treated by subtotal resection survived more than five years with postopertive radiotherapy.