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Ovarian granulocytic sarcoma as the primary manifestation of acute infantile myelomonocytic leukemia
Author(s) -
Morgan Elaine R.,
Labotka Richard J.,
GonzalezCrussi Frank,
Wiederhold Mark,
Sherman Joseph O.
Publication year - 1981
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19811015)48:8<1819::aid-cncr2820480819>3.0.co;2-6
Subject(s) - medicine , differential diagnosis , pathology , bone marrow , sarcoma , acute myelomonocytic leukemia , leukemia , anemia , biopsy , ovary , immunology
The first known instance of granulocytic sarcoma of the ovary as the presenting manifestation of acute nonlymphocytic leukemia in infancy is reported. The clinical and laboratory findings for a 3‐month‐old infant who had anemia and a lower abdominal mass subsequently found to represent bilateral ovarian granulocytic sarcomas are discussed. Results of light and electron microscopic examination of bone marrow biopsy specimen were consistent with a diagnosis of acute myelomonocytic leukemia. Hematopoietic (and lymphoproliferative) disorders must be included in the differential diagnosis of ovarian masses in children.