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Human breast cancer: Heterogeneity of estrogen binding sites
Author(s) -
Poulsen H. Skovgaard,
Jensen J.,
Hermansen C.
Publication year - 1981
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19811015)48:8<1791::aid-cncr2820480816>3.0.co;2-y
Subject(s) - medicine , breast cancer , estrogen receptor , malignancy , estrogen , cancer , oncology , cancer research , pathology
A patient who had two primary tumors in the same breast is described. Both tumors were infiltrating duct carcinomas, but they differed as far as histologic malignancy and estrogen‐receptor‐positivity are concerned. One tumor was estrogen‐receptor‐positive the other was estrogen‐receptor‐negative. The case illustrates the multicentric origin of breast cancer as well as its cellular heterogeneity. Problems of treatment are discussed.