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Prostatic‐specific antigen: An immunohistologic marker for prostatic neoplasms
Author(s) -
Nadji Mehrdad,
Tabei Seyed Z.,
Castro Albert,
Chu T. Ming,
Murphy Gerald P.,
Wang Ming C.,
Morales Azorides R.
Publication year - 1981
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19810901)48:5<1229::aid-cncr2820480529>3.0.co;2-l
Subject(s) - medicine , antigen , prostate specific antigen , pathology , prostatic diseases , prostate , urology , cancer , immunology
Antiserum to a human prostate‐specific antigen was raised in a rabbit and utilized by immunoperoxidase staining to evaluate its potential value as a diagnostic histologic marker for tumors of prostatic origin. All primary and metastatic prostatic malignancies reacted positively, whereas nonprostatic neoplasms did not stain with this procedure. This is the first immununohistochemical marker for prostate gland epithelium which does not represent prostatic acid phosphatase.