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Sideroblastic anemia assOCIATED WITH HAIRY CELL LEUKEMIA
Author(s) -
Martelli Massimo F.,
Falini Brunangelo,
Rambotti Pietro,
Tonato Maurizio,
Davis Stephen
Publication year - 1981
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19810801)48:3<762::aid-cncr2820480317>3.0.co;2-5
Subject(s) - hairy cell leukemia , medicine , hairy cell , leukemia , bone marrow , sideroblastic anemia , anemia , haematopoiesis , immunology , platelet , cell , pathology , cancer research , stem cell , biology , microbiology and biotechnology , biochemistry
A patient with leukemic reticuloendotheliosis (“hairy cell” leukemia) with sideroblastic anemia and an epinephrine‐induced platelet‐aggregation abnormality is presented. Immunologic membrane marker studies supported a B‐lymphocyte origin of the hairy cells. It is hypothesized that a defect in the pluripotent marrow stem cell may be responsible for the hairy cell leukemia and for the intrinsic abnormalities in erythrocytes and platelets.