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Osteogenic sarcoma following Hodgkin's disease
Author(s) -
Niebrugge Daniel,
Monzon Carlos,
Perry Michael C.,
Hakami Nasrollah
Publication year - 1981
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19810715)48:2<416::aid-cncr2820480233>3.0.co;2-h
Subject(s) - medicine , sarcoma , femur , disease , osteosarcoma , chemotherapy , cancer , oncology , pathology , surgery
The cases of two children who developed osteogenic sarcoma of the distal femur following prolonged remission of Hodgkin's disease are reported. These cases are unique in that the sarcoma developed in an area not previously irradiated. This occurrence suggests the possibility of genetic susceptibility to primary cancers in certain individuals, although prior chemotherapy may have contributed to this occurrence.