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Ovarian tumor as manifestation of relapse in acute lymphoblastic leukemia
Author(s) -
Chu JenYih,
Cradock Thomas V.,
Danis Richard K.,
Tennant Nancy E.
Publication year - 1981
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19810715)48:2<377::aid-cncr2820480225>3.0.co;2-6
Subject(s) - medicine , bone marrow , chemotherapy , leukemia , lymphoblastic leukemia , infiltration (hvac) , surgery , physics , thermodynamics
Abstract Acute lymphoblastic leukemia (ALL) was initially diagnosed in a 12‐year‐old girl. Maintenance chemotherapy was discontinued after 32 months of continuous remission. Relapse of ALL occurred ten months after cessation of chemotherapy. Twenty‐one months after relapse, she presented with a large ovarian tumor due to leukemic infiltration while her bone marrow and central nervous system (CNS) were still in remission. She remained in bone marrow and CNS remission when disseminated leukemic infiltration of the peritoneum was found seven months later. She died of bone marrow relapse 11 months after ovarian relapse, six years and two months after the initial diagnosis. In contrast to testicular relapse, ovarian relapses in acute lymphoblastic leukemia are rarely reported.