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Management of Hodgkin's disease in a patient with sickle cell anemia
Author(s) -
Salmassi Sadegh,
Currie Evelyn Taylor,
Bolf Edward C.,
Hernandez Maria,
Kasprisin Duke O.
Publication year - 1981
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19810715)48:2<252::aid-cncr2820480207>3.0.co;2-m
Subject(s) - medicine , anemia , disease , laparotomy , lymphoproliferative disorders , splenectomy , surgery , pediatrics , lymphoma , spleen
A right periauricular swelling developed in a 21‐year‐old woman with sickle cell anemia. The mass was removed and revealed Hodgkin's disease of the lymphocyte predominance type. While preparing the patient for a staging laparotomy, an allo‐anti‐Kell and an allo‐antic‐C were identified in the patient's sera. The patient's direct antiglobulin test was positive and an auto‐anti‐e was eluted from the patient's erythrocytes. The patient was treated with nine courses of MOPP therapy given over a nine‐month period. The clinical and therapeutic implications for the management of patients with sickle cell anemia and lymphoproliferative disorders are discussed.