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Angioimmunoblastic lymphadenopathy: A study of the function of lymphocyte populations
Author(s) -
Garam Tamás,
Bak Mihály,
Bakács Tibor,
Döbrentei Eszter,
Petrányi Győző
Publication year - 1981
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19810615)47:12<2850::aid-cncr2820471217>3.0.co;2-g
Subject(s) - medicine , pathology , lymphocyte , lymph node , cytotoxicity , immunology , biology , in vitro , biochemistry
The case of a 57‐year‐old woman with the diagnosis of angioimmunoblastic lymphadenopathy (AILD) is reported. During the 15 years of the disease, no malignant transformation had been detected. The clinical picture is unusual in certain respects. Lymph node manifestation had been preceded by extraglandular AILD infiltrates. All histologic materials showed a picture typical of AILD. A functional study of peripheral lymphocyte subpopulations revealed decreased natural cytotoxicity and decreased T‐lymphocyte activity.