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Human pancreatic cancer: Analysis of proteins contained in pancreatic juice by two‐dimensional isoelectric focusing/sodium dodecyl sulfate gel electrophoresis
Author(s) -
Scheele George A.
Publication year - 1981
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19810315)47:6+<1513::aid-cncr2820471412>3.0.co;2-l
Subject(s) - isoelectric focusing , sodium dodecyl sulfate , gel electrophoresis , pancreatic juice , pancreatic cancer , electrophoresis , medicine , isoelectric point , biochemistry , cancer , sodium , chromatography , pancreas , chemistry , enzyme , organic chemistry
Nineteen discrete proteins contained in normal human pancreatic juice were separated by two‐dimensional isoelectric focusing/SDS gel electrophoresis. Enzyme or proenzyme activity was assigned to 15 of these proteins. Analysis of pancreatic juice obtained from a patient with pancreatic cancer showed a number of additional proteins not observed in pancreatic juice obtained from normals.