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Malignant lymphoma presenting in the orbit: A clinicopathologic study of a rare immunoglobulin‐producing variant
Author(s) -
Brisbane Jane U.,
Lessell Simmons,
Finkel Harvey E.,
Neiman Richard S.
Publication year - 1981
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19810201)47:3<548::aid-cncr2820470321>3.0.co;2-o
Subject(s) - medicine , paraproteinemia , lymphoplasmacytic lymphoma , pathology , lymphoma , antibody , orbit (dynamics) , amyloidosis , immunoglobulin light chain , malignant lymphoma , immunoglobulin m , immunoglobulin g , multiple myeloma , waldenstrom macroglobulinemia , immunology , engineering , aerospace engineering
Malignant lymphoma with orbital presentation and associated serum paraproteinemia has seldom been reported in the literature. We report two such cases of lymphoplasmacytic type, one of which was also associated with amyloidosis. Both cases were studied with immunohistologic and one with electron microscopic techniques with results that confirmed that the neoplastic cells were producing the abnormal serum immunoglobulin.