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Nasopharyngeal carcinoma—a retrospective review of patients less than thirty years of age: A report from childrens cancer study group
Author(s) -
Jenkin R. Derek T.,
Anderson James R.,
Jereb Berta,
Thompson John C.,
Pyesmany Alan,
Wara William M.,
Hammond Denman
Publication year - 1981
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19810115)47:2<360::aid-cncr2820470225>3.0.co;2-3
Subject(s) - medicine , nasopharyngeal carcinoma , retrospective cohort study , cancer , carcinoma , pediatrics , surgery , radiation therapy
Data from 119 patients with nasopharyngeal carcinoma who were under 30 years of age were retrospectively analyzed by the investigators of the Childrens Cancer Study Group. The overall five‐year survival and relapse‐free survival rates from diagnosis were 51 and 36%, respectively. When the tumor was confined to the nasopharynx (T1 + T2, 41 patients), the five‐year survival was 75%. No significant correlation was found between survival or local recurrence and the radiation dose to the primary site. The five‐year survival from relapse was 37% for 21 reirradiated patients with local and/or regional relapse compared with 11% for 45 patients with other forms of relapse. It is concluded that the optimal radiation dose for tumor eradication in young patients is not known.