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Cryptococcosis and multiple squamous cell tumors associated with a T‐cell defect
Author(s) -
Heenan P. J.,
Dawkins R. L.
Publication year - 1981
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19810115)47:2<291::aid-cncr2820470214>3.0.co;2-4
Subject(s) - cryptococcosis , medicine , pathology , cell , cryptococcus neoformans , immunity , immunology , biology , immune system , microbiology and biotechnology , genetics
A 54‐year‐old male with multiple squamous cell tumors was shown to have capsule deficient cryptococcosis confined to bone. Further investigations revealed a severe defect of cell‐mediated immunity and the presence of serum antinuclear factor. An underlying T‐cell defect might explain the unusual cryptococcal infection and the extremely aggressive behavior of the skin tumors.