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Malignant lymphoma of the thyroid gland with plasma cell differentiation (plasmacytoma)
Author(s) -
Buss David H.,
Marshall Richard B.,
Holleman Ivan L.,
Myers Richard T.
Publication year - 1980
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19801215)46:12<2671::aid-cncr2820461222>3.0.co;2-2
Subject(s) - plasmacytoma , pathology , lymphoma , thyroid , medicine , lymphatic system , plasma cell neoplasm , plasma cell , neoplasm , histiocyte , sarcoma , bone marrow , multiple myeloma
An unusual case of malignant lymphoma of the thyroid is reported. The predominant appearance of the neoplasm was that of a large cell (“histiocytic”) lymphoma, but a discrete portion of the tumor showed features typical of plasmacytoma. Electron microscopy revealed a wide spectrum of cell types, ranging from very immature lymphoid cells to relatively well‐developed plasma cells. The findings support the concept that the neoplastic process represents an immunoblastic sarcoma composed of proliferating transformed B lymphocytes (immunoblasts) and their progeny (plasma cells) rather than two distinct lymphoid neoplasms occurring simultaneously.