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Pulmonary manifestations of mycosis fungoides
Author(s) -
Wolfe James D.,
Trevor Everett D.,
Kjeldsberg Carl R.
Publication year - 1980
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19801215)46:12<2648::aid-cncr2820461219>3.0.co;2-1
Subject(s) - mycosis fungoides , medicine , autopsy , atelectasis , pathology , lung , biopsy , mycosis , skin biopsy , lung biopsy , lymphoma , surgery
Three patients with mycosis fungoides who developed pulmonary abnormalities are described. These abnormalities are correlated with the findings at open lung biopsy and at autopsy. The roentgenographic changes consisted of bilateral, nodular pulmonary infiltrates in two patients, and interstitial infiltrate and plate‐like atelectasis with hilar adenopathy in a third patient. Examination of lung biopsies and autopsy tissue revealed interstitial and/or intra‐alveolar infiltrates composed of atypical lymphoid cells similar to those seen in the skin biopsies. The short survival after detection of an abnormal chest film suggests that dissemination of mycosis fungoides to the lung heralds a poor prognosis.