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The problem of nonresponding estrogen receptor‐positive patients with advanced breast cancer
Author(s) -
Maass Heinrich,
Jonat Walter,
Stolzenbach Gunther,
Trams Gunther
Publication year - 1980
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19801215)46:12+<2835::aid-cncr2820461420>3.0.co;2-m
Subject(s) - medicine , estrogen receptor , breast cancer , estrogen , endocrine system , cancer , receptor , oncology , physiology , hormone
Patients with advanced breast cancer and low or poor concentration of estrogen receptors in tumor biopsies have little chance of responding to endocrine therapy. This problem was seen in a group of nonresponding estrogen receptor‐positive (ER+) patients. Some comments on possible explanations for this phenomenon are made and suggestions to overcome it are given.