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Peripheral neuroepithelioma: A light and electron microscopic study
Author(s) -
Bolen John W.,
Thorning David
Publication year - 1980
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19801201)46:11<2456::aid-cncr2820461126>3.0.co;2-v
Subject(s) - medicine , pathology , biopsy , ultrastructure , lesion , lumbosacral joint , peripheral nerve , peripheral , electron microscope , glycogen , anatomy , physics , optics
A primitive neuroectodermal tumor of peripheral nerve origin was examined by light and electron microscopy. The lesion arose in association with the SI nerve root of the lumbosacral plexus in a 22‐year‐old female. Following a surgical biopsy, the patient received systemic chemotherapy; however, approximately one‐and‐a‐half years later, she suffered a clinical relapse with locally recurrent tumor. An excisional biopsy was performed, and pathologic examination revealed progressive neuroblastic differentiation. The ultrastructural features of neoplastic Homer‐Wright rosettes will be illustrated, and the non‐specificity of cytoplasmic glycogen in the evaluation of „small round cell neoplasms” will be emphasized.