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Pulmonary lymphangiomyomatosis: Treatment with castration
Author(s) -
Kitzsteiner Kristen A.,
Mallen Robert G.
Publication year - 1980
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19801115)46:10<2248::aid-cncr2820461022>3.0.co;2-5
Subject(s) - medicine , castration , disease , respiratory system , shunt (medical) , respiratory failure , rare disease , respiratory disease , pregnancy , hormone , surgery , intensive care medicine , lung , biology , genetics
Pulmonary lymphangiomyomatosis (PLM) is a rare disease of smooth muscle proliferation that generally leads to an early death due to respiratory insufficiency. The disease only affects women. Exacerbations with pregnancy and after hormonal manipulation have been documented. There is presently no successful treatment of the disease. Castration as a means of early therapy has been associated with a stable respiratory picture in our patient. Peritoneal‐jugular shunt can benefit women with significant ascities.