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Bone Marrow Necrosis
Author(s) -
Cowan John D.,
Rubin Ronald N.,
Kies Merrill S.,
Cerezo Lizardo
Publication year - 1980
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19801115)46:10<2168::aid-cncr2820461011>3.0.co;2-a
Subject(s) - pancytopenia , medicine , bone marrow , necrosis , pathology , autopsy , lymphoma , chemotherapy
Extensive bone marrow necrosis is an unusual histologic finding most commonly identified after autopsy. We describe a patient with poorly differentiated lymphocytic lymphoma who manifested pancytopenia and marrow necrosis. Bone marrow scanning with 99m Tc‐sulfur‐minicolloid provided a noninvasive means to assess the extent of marrow damage. Our patient's condition improved clinically following cytotoxic chemotherapy demonstrating that marrow necrosis may be associated with a treatable disease.