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Granulomatous hepatitis as a late complication of BCG immunotherapy
Author(s) -
Flippin Tony,
Mukherji Bijay,
Dayal Yogeshwar
Publication year - 1980
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19801015)46:8<1759::aid-cncr2820460810>3.0.co;2-6
Subject(s) - medicine , immunotherapy , complication , bcg vaccine , granulomatous disease , hepatitis , melanoma , granuloma , chemotherapy , immunology , disease , vaccination , dermatology , pathology , immune system , surgery , cancer research
A case of BCG‐induced granulomatous hepatitis, which developed 1 1/2 years after BCG immunotherapy for recurrent malignant melanoma, is described to document the development of this disease entity as a potential late complication of BCG immunotherapy. The clinical implications of the late development of BCG‐induced granulomatous hepatitis, use of immunosuppressive chemotherapy, and possible alternatives for BCG in intratumor immunotherapy are discussed.