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A family with Peutz‐Jeghers syndrome and bilateral breast cancer
Author(s) -
Riley Elizabeth,
Swift Michael
Publication year - 1980
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19800815)46:4<815::aid-cncr2820460428>3.0.co;2-v
Subject(s) - peutz–jeghers syndrome , medicine , proband , breast cancer , cancer , ovarian cancer , oophorectomy , oncology , gynecology , obstetrics , pathology , hysterectomy , gene , biochemistry , chemistry , mutation
The proband and her paternal grandmother had bilateral breast carcinoma and the Peutz‐Jeghers syndrome. An ovarian sex cord tumor with annular tubules was an incidental finding when oophorectomy was performed as treatment of the proband's premenopausal breast cancer. Because there are previous reports of breast cancer in patients with this syndrome, the Peutz‐Jeghers gene may be associated with an increased risk of breast tumors.