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Intracranial plasma cell granuloma
Author(s) -
West Sterling G.,
Pittman David L.,
Coggin Julian T.
Publication year - 1980
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19800715)46:2<330::aid-cncr2820460220>3.0.co;2-m
Subject(s) - plasma cell granuloma , plasma cell , pathology , granuloma , polyclonal antibodies , medicine , electron microscope , immunology , antibody , lesion , bone marrow , physics , inflammatory pseudotumor , optics
The first case of an intracranial plasma cell granuloma is presented. An associated polyclonal gammopathy was another remarkable feature. Routine and special stains of histologic sections as well as electron microscopy characterized such lesions. Immunofluorescent studies revealed a heterogeneous population of plasma cells. When the granuloma was removed, the polyclonal gammopathy resolved, and neither have recurred with eight months of follow‐up. It is suggested that prior reports of meningiomas with conspicuous plasma cell‐lymphocytic components may in reality be plasma cell granulomas and could be differentiated by electron microscopy.