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Tobacco‐induced changes in oral leukoplakic epithelium
Author(s) -
Pindborg J. J.,
Reibel J.,
RoedPetersen B.,
Mehta F. S.
Publication year - 1980
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19800501)45:9<2330::aid-cncr2820450916>3.0.co;2-r
Subject(s) - medicine , leukoplakia , chewing tobacco , biopsy , precancerous condition , epithelium , oral leukoplakia , pathology , snuff , cancer , dermatology
A study of 112 biopsy specimens from Danish oral leukoplakia patients and 145 biopsy specimens from Indian leukoplakia patients revealed a chevron‐like keratinization of the epithelium in a number of cases. Clinically, this type of keratinization was often characterized by a pumice‐like appearance. The clinical and histologic changes were only observed in tobacco users, and appeared to be associated particularly with use of pipes, snuff, and hooklis.