Premium
Accidental intramuscular injection of mechlorethamine
Author(s) -
Owen Oliver E.,
Dellatorre Daniel L.,
van Scott Eugene J.,
Cohen Michael R.
Publication year - 1980
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19800415)45:8<2225::aid-cncr2820450836>3.0.co;2-8
Subject(s) - medicine , intramuscular injection , sodium thiosulfate , accidental , tenderness , surgery , injection site , anesthesia , inorganic chemistry , chemistry , physics , acoustics
A 55‐year‐old man with chronic, active, diffuse psoriasis was accidentally given 30 mg of mechlorethamine deep into the buttock muscles. About 5 hours after the intramuscular (IM) mechlorethamine injection, 1/6 M sodium thiosulfate was infused around the intramuscular site. Although systemic responses to the mechlorethamine developed, the expected muscular and adjacent skin destruction did not occur. Instead, IM mechlorethamine induced only minimal local tenderness.