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Hemoglobin F production in testicular malignancy
Author(s) -
Dainiak Nicholas,
Hoffman Ronald
Publication year - 1980
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19800415)45:8<2177::aid-cncr2820450828>3.0.co;2-w
Subject(s) - malignancy , medicine , hemoglobin , endocrinology , gastroenterology
The peripheral blood of 3 patients with testicular malignancy and elevated hCG levels was examined for Hb F production. Increases of percent chemically determined Hb F and/or F cell number were observed in each case when or soon after the hCG level was elevated. In these cases, Hb F production correlated with the degree of clinically evident malignancy. These observations suggest that the reactivation of Hb F synthesis may be applied to the evaluation of disease activity in patients with testicular malignancy.