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A pathological survey of intracranial Germinoma and Pinealoma in Japan
Author(s) -
Koide Osamu,
Watanabe Yonosuke,
Sato Kazuyoshi
Publication year - 1980
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19800415)45:8<2119::aid-cncr2820450820>3.0.co;2-j
Subject(s) - pinealoma , germinoma , medicine , dysgerminoma , pathology , teratoma , radiation therapy , radiology , ovary
Pathologic survey was performed on 43 cases of intracranial germinoma and 12 cases of pinealoma. The present study suggests that, in Japan, the incidence of teratoma groups including germinoma is remarkably higher than that in U.S. and Europe, whereas the rate of true pinealoma is lower. Using ultrastructural, enzyme‐histochemical, and fluorescence‐histochemical methods for a few surgical specimens, a strong similarity between intracranial germinoma (so‐called “pinealoma” with a two‐cell pattern) and seminoma and dysgerminoma was confirmed. The true pinealoma could be classified as pineoblastoma and pineocytoma, according to the degree of pineocytic differentiation of the tumor cells, and as “neuroblastoma‐like” and “pineal‐like” on the basis of the histologic architecture.