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Wilms' tumor in the adult patient. Diagnosis, management, and review of the world medical literature
Author(s) -
Babaian Richard J.,
Skinner Donald G.,
Waisman Jerry
Publication year - 1980
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19800401)45:7<1713::aid-cncr2820450732>3.0.co;2-u
Subject(s) - wilms' tumor , medicine , disease , neoplasm , stage (stratigraphy) , childhood cancer , pathology , multimodal therapy , pediatrics , cancer , surgery , paleontology , biology
Adult Wilms' tumor, unlike that of childhood, is a rare disease. A total of 167 cases have been reported in the world medical literature. However, there is controversy as to whether all of these are indeed truly nephroblastomas or in actuality represent sarcomatoid renal carcinomas. The pathologic hallmarks of this neoplasm are distinctive and it is histologically similar to the childhood tumor. The therapeutic guidelines and surgical principles that govern childhood Wilms' tumor should be applied to adult Wilms' tumor. Aggressive and multimodal therapy should be the hallmark of management of this rare neoplasm. Three well documented cases of Wilms' tumor in the adult patient are presented. Of these three patients, two who presented with Stage IV disease and were treated with multimodal therapy were rendered free of disease, one living at 24 months and the other dead at five months.