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Anaplastic giant and spindle‐cell carcinoma of the thyroid. A different therapeutic approach
Author(s) -
Casterline Peter F.,
Jaques Darrell A.,
Blom Hans,
Wartofsky Leonard
Publication year - 1980
Publication title -
cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.052
H-Index - 304
eISSN - 1097-0142
pISSN - 0008-543X
DOI - 10.1002/1097-0142(19800401)45:7<1689::aid-cncr2820450728>3.0.co;2-s
Subject(s) - medicine , chemotherapy , carcinoma , immunotherapy , thyroid , therapeutic approach , anaplastic carcinoma , thyroid cancer , cancer , therapeutic modalities , thyroid carcinoma , oncology , surgery , radiology , pathology , disease
The prognosis of giant and spindle cell carcinoma of the thyroid is extremely poor. It does appear, however, that a multidisciplinary approach to treatment of this aggressive cancer is more effective than a single‐treatment modality. Operative ablation of gross tumor, postoperative irradiation therapy, and chemotherapy have demonstrated encouraging results. A different therapeutic approach with the addition of immunotherapy to surgical resection, postoperative irradiation, and chemotherapy is described in this case report. The preliminary result is encouraging.